Department of Biology
Loyola University Maryland
4501 North Charles Street
Baltimore, MD 21210-2699
Office: DS 242
Office tel: 410-617-5244
Areas of Interest
Reproductive Physiology and Forensic Entomology
A.B - Ripon College, Ripon Wisconsin (Major: Biology, Minor: Chemistry)
Ph.D. - University of Wisconsin-Milwaukee
Postdoctoral Fellowship – Oregon Regional Primate Research Center
Research done in my laboratory is very collaborative in nature. I am involved in a number of research projects, dividing along two main lines of interest. I am interested in the intersection of metabolism and reproduction. While doing my postdoctoral fellowship at the Oregon Primate Center, I was involved studies trying to determine how energy load translated into neuronal activation of the brain areas that control reproduction. I was very interested in how certain hormones, mainly leptin, regulated distinct parts of the brain that were involved in ingestive (or eating) behavior and reproductive ability. Since coming to Loyola, I have maintained that interest and expanding to trying to understand how hormones from the adipose tissue (now termed adipokines) regulate specific processes in the ovary. For these projects, my collaborators and I use non-human primates as our model. Specifically, we are looking at how the adipokines potentially regulate glucose and in turn how changes in glucose and lipid metabolism then regulate the process of ovulation and potentially the development of the oocyte.
The second line of interest comes mainly from reading forensic detective novels. I have always loved the books written by Patricia Cornwell (and others). Stories referring to detectives using forensic and medical evidence to solve puzzles and sometimes crimes are quite fun to read and interesting to me. So, when presented with the opportunity to do some actual research on methods that forensic scientists might someday use, I was hooked. To date I have collaborated with Dr. David Rivers to understand how fly development (flesh flies and blow flies) is regulated when the flies are reared in varying temperatures due to mass density.
Brogan, R.S., VandeVoort, C.A., and C. L. Chaffin. Adiponectin, resistin, and glucose transporters during the periovulatory interval in rhesus macaques. In preparation.
Brogan, R.S.,Goldberg, J., VandeVoort C.A., and C. L. Chaffin. Intra-ovarian regulation of the opioid system in primates. In preparation
O. Zurek, J. Jacobi, C. DeFelice, L. Dybas, R. Brogan, and C. Thompson. Macrophage Cannabinoid Receptor 2 is Critical to Echinacea-Induced Microbicidal Activity and IL-10 Secretion. Submitted and in revision
David B. Rivers, Gregory Cavanagh, Valerie Greisman, Andrew McGregor, Rebecca Brogan, Andrew Schoeffield. 2019. Immunoassay detection of fly artifacts produced by several species of necrophagous flies following feeding on human blood. Forensic Science International: Synergy
Volume 1, 2019, Pages 1-10.
David B. Rivers; Gillian Acca; Marc Fink; Rebecca Brogan; Dorothy Chen; and Andrew Schoeffield Distinction of fly artifacts from human blood using immunodetection. Manuscript in preparation for Journal of Forensic Sciences Pathology/Biology. Published Early View February 21, 2018.
Rivers DB, Acca G, Fink M, Brogan R, Schoeffield A. 2014. Spatial characterization of proteolytic enzyme activity in the foregut region of the adult necrophagous fly, Protophormia terraenovae. J Insect Physiol. Aug; 67:45-55. doi: 10.1016/j.jinsphys.2014.06.006.
C.R. Thompson, R.S. Brogan, and D. B. Rivers. 2013. Bacterial Interactions with Necrophagous Flies. Annals of the Entomological Society of America, 106(6), 799-809.
Puttabyatappa, M., Brogan, R.S., VandeVoort, C.A., and C.L. Chaffin. 2013. EGF-like ligands mediate progesterone’s anti-apoptotic action on macaque granulosa cells. Biol Reprod vol 88, Issue 1 (Jan 2013) pp1-10.
David B. Rivers*, Andreas Kaikis, Daniel Bulanowski, Timothy Wigand and Rebecca Brogan
2012. Oviposition restraint and developmental alterations in the ectoparasitic wasp Nasonia vitripennis (Walker) when utilizing puparia resulting from different size maggot masses of Lucilia illustris, Protophormia terraenovae and Sarcophaga bullata. Journal of Medical Entomology 49(5): 1124-1236.
If you are interested in these types of research, you might also find the following people interesting as well:
M. Susan Smith, Oregon Regional Primate Research Center and Oregon Health Sciences University
Bill Bass and Jon Jefferson, The Body Farm